Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts

Autor:	Gianluca Casotti, Graziano Fusini, Claudio Evangelisti, Matteo Ferreri, Luca Pardini, Adriano Carpita, Gaetano Angelici
Rok vydání:	2020
Předmět:	Sonogashira cross-coupling Chemistry Natural compound Organic Chemistry Total synthesis Sonogashira coupling Asparenydiol Combinatorial chemistry Mitsunobu etherification Catalysis Coupling reaction solid-supported palladium catalyst Catalytic efficiency total synthesis
Zdroj:	Synthesis (Stuttg.) 52 (2020): 1795–1803. doi:10.1055/s-0039-1690852 info:cnr-pdr/source/autori:Casotti G.; Fusini G.; Ferreri M.; Pardini L.F.; Evangelisti C.; Angelici G.; Carpita A./titolo:Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts/doi:10.1055%2Fs-0039-1690852/rivista:Synthesis (Stuttg.)/anno:2020/pagina_da:1795/pagina_a:1803/intervallo_pagine:1795–1803/volume:52
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0039-1690852
Popis:	Asparenydiol, which is an important natural compound with potential pharmacological activities, was synthesized through two Sonogashira­ cross-coupling reactions catalyzed by supported Pd and Cu catalysts and by a Mitsunobu etherification. The optimization of the Sonogashira­ couplings allowed the use of catalysts supported on different matrices with good results in terms of catalytic efficiency and yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe07e6d7d9604e6aee6a2010faf9f4e6 https://doi.org/10.1055/s-0039-1690852 Zobrazit plný text záznamu