Radioiodination of Modified Porous Silica Nanoparticles as a Potential Candidate of Iodine-131 Drugs Vehicle

Autor: Maria Christina Prihatiningsih, Teguh Ariyanto, Edy Giri Rachman Putra, Veronika Yulianti Susilo, Isa Mahendra, Imam Prasetyo
Rok vydání: 2022
Předmět:
Zdroj: ACS Omega. 7:13494-13506
ISSN: 2470-1343
DOI: 10.1021/acsomega.1c06492
Popis: There are challenges related to cancer treatment, namely, targeting and biocompatibility associated with a drug vehicle. This research aims to prepare a theranostic cancer vehicle based on porous silica nanoparticles (PSN) with controllable nanoparticle size, supporting targeting properties, and biocompatible. The synthesis method combined the Stöber process and liquid crystal templating using a dispersant and pore expander. Triethanolamine (TEA) and Pluronic F-127 were combined as a steric stabilizer and dispersing agent, while
Databáze: OpenAIRE