Ileal transposition in surgical treatment for type 2 diabetes mellitus
| Autor: | Mikhail Michailovich Galagudza, Alina Yur'evna Grineva, Alexander Evgen'evich Neymark, Oleg Viktorovich Kornyushin, Elena Nikolaevna Babenko |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
RC620-627 endocrine system diseases Endocrinology Diabetes and Metabolism bariatric surgery Incretin Endocrinology Diabetes mellitus Internal medicine Internal Medicine medicine Surgical treatment Nutritional diseases. Deficiency diseases High prevalence Ileal transposition Medical treatment business.industry Type 2 Diabetes Mellitus nutritional and metabolic diseases medicine.disease Surgery Clinical trial diabetes mellitus ileal transposition business incretins |
| Zdroj: | Сахарный диабет, Vol 18, Iss 1, Pp 58-64 (2015) |
| ISSN: | 2072-0378 2072-0351 |
| Popis: | High prevalence and insufficient efficacy of medical treatment in type 2 diabetes mellitus (T2DM) poses a major challenge for medical care. Generally, only 30% of patients reach therapeutic goals, while remission occurs only in the minority of patients. In the obese (BMI>35 kg/m2), bariatric surgery provides an alternative to pharmacological treatment of T2DM, boosting remission/compensation rate up to 76.8%. A few recent clinical studies explored the anti-diabetic effect of ileal transposition (IT). This type of surgery targets restoration of incretin balance by proximal transposition of ileal segment. In this review, we discuss the salutary mechanisms of IT in T2DM based on the analysis of the pioneering clinical trials. |
| Databáze: | OpenAIRE |
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