Should microcirculation monitoring be used to guide fluid resuscitation in severe sepsis and septic shock?

Autor: Gustavo A. Ospina-Tascón, Humberto Madriñán-Navia
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Revista Brasileira de Terapia Intensiva
Repositorio ICESI
Universidad ICESI
instacron:Universidad ICESI
Revista Brasileira de Terapia Intensiva, Volume: 27, Issue: 2, Pages: 92-95, Published: JUN 2015
ISSN: 1982-4335
0103-507X
Popis: However, how to identify organ perfusion abnormalities at the bedside and select the type and amount of fluids required to improve tissue hypoxia remain highly controversial. Traditionally, clinical signs, such as reduced blood pressure and urinary output, altered consciousness, and mottled skin, have been used to identify tissue perfusion abnormalities. Consequently, current hemodynamic monitoring during shock states mainly focuses on detection of pressure-derived hemodynamic variables related to systemic circulation. However, it has been largely recognized that monitoring these macro-hemodynamic variables is not sufficient to rule out persistent abnormalities of tissue oxygenation. Indeed, the usefulness of resuscitation targets, such as global oxygen-derived parameters, has been strongly questioned
Databáze: OpenAIRE