Left ventricular inflow propagation velocity at pulsed wave Doppler analysis: An index of relaxation
| Autor: | Ming-Yi Lee, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu, Ho-Ming Su, Chien-Tsai Lin, Tsung-Hsien Lin, Hsueh-Wei Yen |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Cardiac Catheterization medicine.medical_specialty medicine.medical_treatment Inflow Chest pain Nitroglycerin Ventricular Dysfunction Left symbols.namesake Heart Rate Internal medicine Heart rate medicine Humans Radiology Nuclear Medicine and imaging Cardiac catheterization Echocardiography Doppler Pulsed business.industry Time constant Middle Aged symbols Cardiology Ventricular pressure Relaxation (physics) Female medicine.symptom Cardiology and Cardiovascular Medicine business Doppler effect Blood Flow Velocity |
| Zdroj: | Journal of the American Society of Echocardiography. 18:326-329 |
| ISSN: | 0894-7317 |
| DOI: | 10.1016/j.echo.2004.10.015 |
| Popis: | To test whether left ventricular inflow propagation velocity at the pulsed wave Doppler analysis (IPVpw) is a useful noninvasive index of relaxation, 21 patients under coronary angiography for chest pain were included for simultaneous catheter-based and Doppler studies. IPVpw was derived through the application of range ambiguity, and the time constant of isovolumic left ventricular pressure decline (tau) was acquired by a previously described method. At baseline status, IPVpw correlated significantly with the peak negative dP/dt and tau ( r = -0.609, P = .003), but not with the peak velocity of transmitral early flow (E) wave. Sublingual application of nitroglycerin increased heart rate, decreased the transmitral E velocity and transmitral E-to-A velocity ratio, and prolonged the deceleration time of the transmitral E wave. However, there was no significant impact on IPVpw, peak negative dP/dt, or tau. IPVpw correlated with tau ( r = -0.533, P.001) at the combined analysis of the data before and after nitroglycerin application. In conclusion, IPVpw is a preload-independent, noninvasive index of left ventricular relaxation. |
| Databáze: | OpenAIRE |
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