Adherence to follow-up examination after positive fecal occult blood test results affects colorectal cancer mortality: A Korea population-based cohort study
| Autor: | Jessie Lee, Duk Hwan Kim, Chang Mo Moon, Minjoo Kang, Eun Jung Park, Yu Jin Kim, Kui Son Choi, Kyeong Ae Kong, Ha Jin Tchoe, Jeong Im Shim, Sinhee Kang, Byung Chang Kim |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Colorectal cancer Colonoscopy 03 medical and health sciences 0302 clinical medicine Internal medicine Cancer screening Republic of Korea medicine Humans Mass Screening Stage (cooking) Survival rate Aged Proportional Hazards Models Retrospective Studies Aged 80 and over Hepatology medicine.diagnostic_test business.industry Incidence (epidemiology) Incidence Fecal occult blood Gastroenterology Retrospective cohort study Middle Aged medicine.disease digestive system diseases 030220 oncology & carcinogenesis Occult Blood Patient Compliance 030211 gastroenterology & hepatology Female business Colorectal Neoplasms Follow-Up Studies |
| Zdroj: | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 53(5) |
| ISSN: | 1878-3562 |
| Popis: | The impact of adherence to follow-up examination after a fecal occult blood test (FOBT) remains ill-defined.To evaluate the impact of adherence to the follow-up examination on clinical outcomes in individuals with positive FOBT results.This was a retrospective cohort study involving Korean individuals aged 50 years or older who participated in the National Cancer Screening Program for CRC from 2009 to 2010. Individuals who underwent a confirmative examination within a year after positive FOBT results were included in compliant group, and those who did not were included in non-compliant group. The incidence and stage of CRC, and 5-year survival were compared between two groups.5,914 were diagnosed with CRC in the compliant group and 2,973 in the non-compliant group. The proportion of advanced-stage CRC was significantly higher in the non-compliant group (localized CRC 44.6% vs. 36.7% and distant CRC 8.7% vs. 12.5%, p0.0001). The survival probability within 5 years was 71.0% in the non-compliant group and 85.9% in the compliant group (hazard ratio 1.70, 95% CI, 1.52-1.90, p0.001).Individuals who underwent follow-up examination 1 year or more after positive FOBT had a lower survival rate compared with that in those who underwent examination within 1 year. |
| Databáze: | OpenAIRE |
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