Iodide-Catalyzed Reductions: Development of a Synthesis of Phenylacetic Acids
| Autor: | Mina Dilmeghani Seran, Jacqueline E. Milne, John T. Colyer, Oliver R. Thiel, Thomas Storz, Robert D. Larsen, Jerry A. Murry |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Molecular Structure Phenylacetates Organic Chemistry Iodide Iodine Compounds Stereoisomerism Phosphorus acid Iodides Mandelic acid Combinatorial chemistry Catalysis chemistry.chemical_compound chemistry Sodium iodide Mandelic Acids Molecule Acids Oxidation-Reduction |
| Zdroj: | The Journal of Organic Chemistry. 76:9519-9524 |
| ISSN: | 1520-6904 0022-3263 |
| DOI: | 10.1021/jo2018087 |
| Popis: | A new convenient and scalable synthesis of phenylacetic acids has been developed via the iodide catalyzed reduction of mandelic acids. The procedure relies on in situ generation of hydroiodic acid from catalytic sodium iodide, employing phosphorus acid as the stoichiometric reductant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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