Impact of patient information leaflets on pain medication intake behavior: a pilot study
Autor: | Janine Wiegratz, Sandra Kamping, Maike Müller, Jan Stork, Regine Klinger, Julia Schmitz, Herta Flor, Luana Colloca |
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Rok vydání: | 2017 |
Předmět: |
medicine.medical_specialty
Nocebo Package insert Patient information leaflet Analgesic Placebo lcsh:RD78.3-87.3 Expectancy 03 medical and health sciences 0302 clinical medicine medicine Psychology 030212 general & internal medicine Expectancy theory Recall business.industry Clinical application Anesthesiology and Pain Medicine Mood lcsh:Anesthesiology cardiovascular system Physical therapy Anxiety lipids (amino acids peptides and proteins) medicine.symptom business 030217 neurology & neurosurgery Research Paper |
Zdroj: | PAIN Reports, Vol 2, Iss 6, p e620 (2017) Pain Reports |
ISSN: | 2471-2531 |
Popis: | Negative wording in package information leaflets of pain medication is associated with a tendency to evoke negative emotions and lower willing to take medication. Introduction: Patient information leaflets on pain medication primarily list side effects while positive effects and action mechanisms remain underrepresented. Nocebo research has shown that negative instructions can lower analgesic effects. Objectives: Research on information leaflets and their influence on mood, memory of side effects, and intake behavior of healthy participants is needed. Methods: To determine the ratio of positive to negative phrases, 18 information leaflets of common, over-the-market analgesics were examined of which 1 was selected. In a randomized, controlled study design, 18 healthy participants read this leaflet while 18 control group participants read a matched, neutral leaflet of an electrical device. Collected data concerned the recall of positive and negative contents, mood, anxiety, and the willingness to buy and take the drug. Results: All examined leaflets listed significantly more side effects than positive effects (t17 = 5.82, P < 0.01). After reading the analgesic leaflet, participants showed a trend towards more negative mood (F1,34 = 3.78, P = 0.06, ηp2 = 0.1), a lower intention to buy [χ2 (1, n = 36) = 12.5, P < 0.01], a higher unwillingness to take the medication [χ2 (1, n = 36) = 7.2, P < 0.01], and even a greater recall for side effects than positive effects (t17 = 7.47, P < 0.01). Conclusion: Reading the patient information leaflets can increase fear and lower the intention to buy and the willingness to take a pain medication. |
Databáze: | OpenAIRE |
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