One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates

Autor: Wei Shi, Wanzhen Li, Jianxin Zhang, Tiehai Li, Yakai Song, Yue Zeng, Qian Dong, Zeng Lin, Likun Gong, Shuquan Fan, Feng Tang, Wei Huang
Rok vydání: 2021
Předmět:
Zdroj: Acta pharmaceutica Sinica. B. 12(5)
ISSN: 2211-3835
Popis: Glycosite-specific antibody‒drug conjugatess (gsADCs), harnessing Asn297
Databáze: OpenAIRE