Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO)

Autor: V. Vassiliou, John Souglakos, Nikolaos Androulakis, Athanasios Athanasiadis, Nikolaos Ziras, Ioannis Pilpilidis, Demetris Papamichael, Ioannis Boukovinas, Nikolaos Gouvas, Paris P. Tekkis, Evaghelos Xynos, Thomas Makatsoris, Ioannis D Kyriazanos, Joseph Sgouros, Panteleimon Kountourakis, Christos Emmanouilidis, Christos Christodoulou, Ourania Katopodi, Maria Tzardi, Georgios Pentheroudakis, Spyridon Xynogalos, Panagiotis Georgiou, Louiza Vini, Evangelia Chrysou, Pavlos Papakostas, Christos Dervenis, Christos Agalianos, Niki Karachaliou, George Sotiropoulos, George Pechlivanides, Charina Triantopoulou
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Annals of Gastroenterology : Quarterly Publication of the Hellenic Society of Gastroenterology
ISSN: 1792-7463
1108-7471
Popis: There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering both special characteristics of our Healthcare System and international guidelines. Following discussion and online communication among the members of an executive team chosen by the Hellenic Society of Medical Oncology (HeSMO), a consensus for metastastic CRC disease was developed. Statements were subjected to the Delphi methodology on two voting rounds by invited multidisciplinary international experts on CRC. Statements reaching level of agreement by ≥80% were considered as having achieved large consensus, whereas statements reaching 60-80% moderate consensus. One hundred and nine statements were developed. Ninety experts voted for those statements. The median rate of abstain per statement was 18.5% (range: 0-54%). In the end of the process, all statements achieved a large consensus. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized. R0 resection is the only intervention that may offer substantial improvement in the oncological outcomes.
Databáze: OpenAIRE