Paulownia C-geranylated flavonoids: their structural variety, biological activity and application prospects
| Autor: | Cheng-mei Xiao, Wen-zhao Tang, Xian-hui Jia, Chun-lei Cheng |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Phytochemistry Natural product biology Traditional medicine fungi food and beverages Paulownia Biological activity Plant Science biology.organism_classification C-geranylated flavonoids 01 natural sciences Article Paulownia species 0104 chemical sciences Biological properties 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Biological property 010606 plant biology & botany Biotechnology |
| Zdroj: | Phytochemistry Reviews |
| ISSN: | 1572-980X 1568-7767 |
| Popis: | Paulownia species, especially their flowers and fruits, are traditionally used in Chinese herbal medicines for the treatment of infectious diseases. C-geranylated flavonoids were found to be the major special metabolites in Paulownia flowers and fruits, and 76 C-geranylated flavonoids had been isolated and characterized thus far. Structural variations in Paulownia C-geranylated flavonoids are mainly due to the complicated structural modifications in their geranyl substituents. These natural compounds have attracted much attention because of their various biological activities, including antioxidation, anti-inflammation, cytotoxic activity and various enzymatic inhibitions, etc. Among them, diplacone, a major Paulownia component, was considered to have promise for applications in medicine. This paper summarizes the information from current publications on Paulownia C-geranylated flavonoids, with a focus on their structural variety, key spectroscopic characteristics, biological activity with structure–activity relationships and application prospects. We hope that this paper will stimulate further investigations of Paulownia species and this kind of natural product. |
| Databáze: | OpenAIRE |
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