Association between obstructive sleep apnea and persistent postural-perceptual dizziness
| Autor: | Jayson Lee Azzi, Darren Tse, Andre Le, Naomi S Spitale, Daniel A Lelli, Anand K Bery, Judith A. Leech |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Polysomnography Sexism Population Polysomnogram Persistent postural perceptual dizziness Dizziness Sensitivity and Specificity Sleep medicine 03 medical and health sciences 0302 clinical medicine Internal medicine Gender bias medicine Humans Stop bang education Sleep Apnea Obstructive education.field_of_study business.industry General Neuroscience Sleep apnea Middle Aged medicine.disease Sensory Systems nervous system diseases respiratory tract diseases Obstructive sleep apnea 030228 respiratory system Otorhinolaryngology Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Vestibular Research. 31:401-406 |
| ISSN: | 1878-6464 0957-4271 |
| DOI: | 10.3233/ves-201508 |
| Popis: | BACKGROUND: Obstructive sleep apnea (OSA) has been linked to vestibular dysfunction, but no prior studies have investigated the relationship between Persistent Postural-Perceptual Dizziness (PPPD), a common cause of chronic dizziness, and OSA. OBJECTIVE AND METHODS: We determined the frequency of OSA in an uncontrolled group of PPPD patients from a tertiary dizziness clinic based on polysomnogram (PSG). We then assessed the sensitivity and specificity of common OSA questionnaires in this population. RESULTS: Twenty-five patients with PPPD underwent PSG (mean age 47, 60% female, mean BMI 29.5). A majority, or 56%, of patients were diagnosed with OSA, and in most, the OSA was severe. OSA patients were older (56 years versus 40 years, p = 0.0006) and had higher BMI (32 versus 26, p = 0.0078), but there was no clear gender bias (56% versus 64% female, p = 1.00). The mean sensitivity and specificity of the STOP BANG questionnaire for detecting OSA was 86% and 55%, respectively. Sensitivity and specificity of the Berlin Questionnaire was 79% and 45%, respectively. CONCLUSIONS: The prevalence of OSA was much higher in our small PPPD group than in the general population. Screening questionnaires appear to demonstrate good sensitivity to detect PPPD patients at risk of OSA in this small study. Future studies should confirm these findings and determine whether treatment of OSA improves symptoms in PPPD. |
| Databáze: | OpenAIRE |
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