Risk factor for cerebrospinal fluid leak after endoscopic endonasal skull base surgery: a single-center experience

Autor:	Yoshihiro Watanabe, Takuya Mikoshiba, Mariko Sekimizu, Shintaro Nakamura, Yuichi Ikari, Kaoru Ogawa, Hiroyuki Ozawa, Masahiro Toda, Shin Saito
Rok vydání:	2021
Předmět:	Adult Male medicine.medical_specialty Adolescent Single Center Skull Base Neoplasms 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Postoperative Complications Risk Factors otorhinolaryngologic diseases medicine Humans Major complication Risk factor 030223 otorhinolaryngology Child Aged Retrospective Studies Aged 80 and over Skull Base Cerebrospinal fluid leak Cerebrospinal Fluid Leak business.industry Incidence Endoscopy General Medicine Middle Aged medicine.disease Surgery Skull medicine.anatomical_structure Otorhinolaryngology Postoperative cerebrospinal fluid leak 030220 oncology & carcinogenesis Skull base surgery Female business
Zdroj:	Acta oto-laryngologica. 141(6)
ISSN:	1651-2251
Popis:	One of the major complications in endoscopic endonasal skull base surgery (EESBS) is postoperative cerebrospinal fluid (CSF) leaks. Recently, EESBS has been applied to various skull base diseases as well as more complicated cases influenced by previous treatment with or without various comorbidities.This study aimed to assess the factors that influence the results of postoperative CSF leak after EESBS with mixed patient backgrounds.We conducted a retrospective analysis of the clinical records of patients undergoing EESBS in our institution from 2012 to 2017.Out of a total of 230 cases of EESBS, 11 (4.8%) suffered from postoperative CSF leakage. The rate of CSF leakage for pituitary adenoma, Rathke's cleft cyst, chordoma, and meningioma was 3.5%, 0%, 3.6% and 8.0%, respectively. Multiple variate analysis revealed that repeated surgery (The rate of postoperative CSF leakage in this study was comparable to previous reports, and repeated surgery may increase postoperative CSF leakage. The surgical strategy for tumor removal as well as skull base reconstruction should be given careful consideration according to tumor pathology and the patient's condition.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd2a1c5a04fb7ba0944e251d023bb4b https://pubmed.ncbi.nlm.nih.gov/33733997 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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