Histone Acetylation by HBO1 Tightens Replication Licensing

Autor:	J. Julian Blow, Gaganmeet Singh Chadha
Rok vydání:	2010
Předmět:	Genetics Histone H4 Control of chromosome duplication Histone H1 Histone H2A Histone code Nucleosome Origin recognition complex Eukaryotic DNA replication Cell Biology Biology Molecular Biology
Zdroj:	Molecular Cell. 37(1):5-6
ISSN:	1097-2765
DOI:	10.1016/j.molcel.2009.12.028
Popis:	In this issue of Molecular Cell, Miotto and Struhl (2010) suggest that replication licensing, the loading of Mcm2-7 onto DNA, is promoted by HBO1 acetylating histone H4 at replication origins, providing a molecular view of how chromatin status influences origin usage.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd1ac047f8f21c52b3b3dff9d2673af Zobrazit plný text záznamu