Correlation between epicardial fat thickness and aortic valve sclerosis
| Autor: | Mozhdeh Dabirian, Maryam Nabati, Maryam Favaedi, Masoud Kheirgoo, Jamshid Yazdani |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Aortic valve sclerosis Heart Valve Diseases Adipose tissue Intra-Abdominal Fat 030204 cardiovascular system & hematology Proinflammatory cytokine 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Adverse effect Visceral fat Adiposity Aged Sclerosis business.industry General Medicine Middle Aged Prognosis medicine.disease Echocardiography Doppler Epicardial fat Aortic Valve Aortic valve stenosis cardiovascular system Cardiology Female Surgery Cardiology and Cardiovascular Medicine business Pericardium |
| Zdroj: | Asian Cardiovascular and Thoracic Annals. 26:188-195 |
| ISSN: | 1816-5370 0218-4923 |
| Popis: | Background Epicardial fat is a true visceral fat deposit with adverse effects through the secretion of numerous proinflammatory and proatherogenic cytokines. Previous studies showed an association between aortic valve sclerosis and coronary artery disease. The aim of this study was to determine the correlation between epicardial fat thickness and aortic valve sclerosis. Method The study involved 225 patients who were admitted for coronary angiography due to new-onset angina. They underwent transthoracic echocardiography and epicardial fat thickness was determined. The sclerosis scoring of each aortic cusp, average aortic valve sclerosis score index, and left ventricular ejection fraction were determined. The variables of left ventricular diastolic function obtained included the early diastolic velocity determined by transmitral pulsed Doppler, and early mitral annular velocity measured by tissue Doppler. Results Patients with an epicardial fat thickness ≥7 mm were older ( p = 0.006), with more hypertension ( p = 0.045) and hyperlipidemia ( p Conclusion Our findings confirm that epicardial fat as a marker of visceral adipose tissue may have an important role in promoting inflammatory and atherosclerotic changes in the aortic valve. |
| Databáze: | OpenAIRE |
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