Aging and the Immune Response to Tetanus Toxoid: Diminished Frequency and Level of Cellular Immune Reactivity to Antigenic Stimulation
| Autor: | Tamir M. Ellis, Eric Jodoin, Eric W. Ottendorfer, Douglas J. Barrett, Desmond A. Schatz, Mark A. Atkinson |
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| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
Microbiology (medical)
Adult Male Aging Adolescent animal diseases Clinical Biochemistry Immunology Population chemical and pharmacologic phenomena complex mixtures Article Immune system Antigenic stimulation Immunity Tetanus Toxoid Immunology and Allergy Medicine Humans education Child Aged education.field_of_study Immunity Cellular business.industry Tetanus Toxoid biochemical phenomena metabolism and nutrition Middle Aged medicine.disease Vaccination Child Preschool Immune reactivity bacteria Female business Immunologic Memory |
| Popis: | The period of efficacious immune reactivity afforded by tetanus immunization and the need for continuing some forms of tetanus vaccination programs have been the subjects of recent debates. Our studies demonstrate that the level of antitetanus immunity based on immunological memory (i.e., cellular immune responsiveness) varies dramatically as a function of age, with older individuals constituting a population which is increasingly susceptible to tetanus infection. |
| Databáze: | OpenAIRE |
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