From prejudice to evidence : the case of Rhizoma Coptidis in Singapore
| Autor: | You Li Goh, Chang Zhang, Chin Ee Ho |
|---|---|
| Přispěvatelé: | School of Biological Sciences |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Traditional medicine
business.industry Rhizoma Coptidis Review Article lcsh:Other systems of medicine Traditional Chinese medicine lcsh:RZ201-999 chemistry.chemical_compound Berberine Science::Biological sciences::Human anatomy and physiology [DRNTU] Complementary and alternative medicine chemistry Chinese community Medicine business |
| Zdroj: | Evidence-Based Complementary and Alternative Medicine, Vol 2014 (2014) Evidence-based Complementary and Alternative Medicine : eCAM |
| Popis: | Rhizoma Coptidis (RC), commonly known ashuanglian, is a herb frequently used in Traditional Chinese Medicine (TCM) prescriptions. Known to have “clearing damp-heat, quenching fire and counteracting poison” properties, it was widely used in the Chinese community in Singapore. Berberine, an alkaloid isolated from RC, is known to have a wide array of therapeutic effects including antimicrobial, antineoplastic, and hepatoprotective effects. In 1978, RC was implicated in causing neonatal jaundice (NNJ) and kernicterus in neonates suffering from glucose-6-phosphate dehydrogenase (G6PD) deficiency, leading to the banning of RC and berberine in Singapore. More than three decades later, accumulating evidence-based studies pointing to the safety of RC for general public and better understanding of G6PD deficiency, the Health Sciences Authority (HSA) in Singapore reviewed and lifted the prohibition on RC and berberine, turning a brand new chapter in the history of TCM in Singapore. This paper aims to review the safety of RC and berberine, using the prohibition of use and subsequent lifting of ban on RC and berberine in Singapore as an illustration to highlight the importance of evidence-based studies in Traditional Chinese Medicine (TCM). |
| Databáze: | OpenAIRE |
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