Calcium imaging and selective computed tomography angiography in comparison to functional testing for suspected coronary artery disease: the multicentre, randomized CRESCENT trial
| Autor: | Adriaan Coenen, Andre Niezen, Jurgen Akkerhuis, Ahno Liem, Marisa Lubbers, Tobias Bruning, Pim J. de Feijter, Boudewijn J. Krenning, Miriam Hunink, Admir Dedic, Tjebbe W. Galema, Mohamed Ouhlous, Paul Musters, Koen Nieman |
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| Přispěvatelé: | Cardiology, Radiology & Nuclear Medicine |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Computed Tomography Angiography Functional testing Coronary Artery Disease Kaplan-Meier Estimate 030204 cardiovascular system & hematology Radiation Dosage 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Electrocardiography 0302 clinical medicine Risk Factors Surveys and Questionnaires Stable cad medicine Myocardial Revascularization Outpatient clinic Humans In patient Vascular Calcification Computed tomography angiography medicine.diagnostic_test business.industry Middle Aged medicine.disease Treatment Outcome Angiography Exercise Test Female Radiology Cardiology and Cardiovascular Medicine business Calcium score |
| Zdroj: | European Heart Journal, 37(15), 1232-1243. Oxford University Press |
| ISSN: | 1522-9645 0195-668X |
| Popis: | Aims To compare the effectiveness and safety of a cardiac computed tomography (CT) algorithm with functional testing in patients with symptoms suggestive of coronary artery disease (CAD). Methods and results Between April 2011 and July 2013, 350 patients with stable angina, referred to the outpatient clinic of four Dutch hospitals, were prospectively randomized between cardiac CT and functional testing (2 : 1 ratio). The tiered cardiac CT protocol included a calcium scan followed by CT angiography if the Agatston calcium score was between 1 and 400. Patients with test-specific contraindications were not excluded from study participation. By 1 year, fewer patients randomized to cardiac CT reported anginal complaints (P = 0.012). The cumulative radiation dose was slightly higher in the CT group (6.6 +/- 8.7 vs. 6.1 +/- 9.3 mSv; P |
| Databáze: | OpenAIRE |
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