Acute Epiglottitis: A Clinical, Bacteriological and Serological Study
| Autor: | Paula Branefors-Helander, Pårl-Henry Jeppsson |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Adult
Male Microbiology (medical) Adolescent Hemagglutination medicine.drug_class medicine.medical_treatment Antibiotics Epiglottis Serology Laryngitis Tracheotomy Antigen Nasopharynx Humans Medicine Child Antigens Bacterial Bacteriological Techniques General Immunology and Microbiology biology business.industry General Medicine Middle Aged medicine.disease Antibodies Bacterial Haemophilus influenzae Trachea Titer Infectious Diseases Child Preschool Acute Disease Immunology biology.protein Female Antibody business Meningitis |
| Zdroj: | Scandinavian Journal of Infectious Diseases. 7:103-111 |
| ISSN: | 1651-1980 0036-5548 |
| DOI: | 10.3109/inf.1975.7.issue-2.05 |
| Popis: | 25 patients, 15 children and 10 adults, with the clinical diagnosis of acute epiglottitis were studied. Patients severely ill on admission, 13 children and 1 adult, were immediately treated with tracheotomy and antibiotics; the remaining patients with antibiotics only. Haemophilus influenzae type b was the causative organism in all children and in 3 adults. One adult had a Diplococcus pneumoniae infection. No pathogens were isolated from the 6 remaining patients. Four of the children developed H. influenzae type b meningitis. All patients recovered. Anti-b antibodies were not demonstrable in any initial serum sample while agglutinating anti-b antibodies were found in subsequent samples (indirect hemagglutination). All patients with a type b infection had already initially precipitating anti-O antibodies against their own strain, and in most cases complement-fixing anti-O antibodies (mixed H. influenzae O antigen) with rising titers in subsequent serum samples. A possible connection between the presence of anti-O antibodies initially and the development of the acute epiglottitis is discussed. |
| Databáze: | OpenAIRE |
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