Preparations of Silver/Montmorillonite Biocomposite Multilayers and Their Antifungal Activity
| Autor: | Luminita Marutescu, A. Groza, Simona Liliana Iconaru, Radu Hristu, Roxana Trusca, George E. Stan, Mihai Ganciu, Daniela Predoi, Patrick Chapon, Carmen Chifiriuc, George A. Stanciu, Liliana Ghegoiu, Teddy Tite, M. L. Badea, Claudiu Stefan Turculet, Sofia Gaiaschi |
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| Rok vydání: | 2019 |
| Předmět: |
antimicrobial activity
Thin layers Materials science Scanning electron microscope multilayers Composite number montmorillonite Surfaces and Interfaces engineering.material Sputter deposition Surfaces Coatings and Films chemistry.chemical_compound Montmorillonite Coating chemistry mental disorders fungal biofilm Materials Chemistry engineering silver Biocomposite Layer (electronics) Nuclear chemistry |
| Zdroj: | Coatings Volume 9 Issue 12 |
| ISSN: | 2079-6412 |
| Popis: | In this study, the results about the influence of the surface morphology of layers based on montmorillonite (MMT) and silver (Ag) on antimicrobial properties are reported. The coating depositions were performed in the plasma of a radio frequency (RF) magnetron sputtering discharge. The studied layers were single montmorillonite layers (MMT) and silver/montmorillonite multilayers (MMT-Ag) obtained by magnetron sputtering technique with a different surface thickness. The resultant MMT-Ag biocomposite multilayers exhibited a uniform distribution of constituent elements and enhanced antimicrobial properties against fungal biofilm development. Glow-discharge optical emission spectroscopy (GDOES) analysis revealed the formation of MMT-Ag biocomposite multilayers following the deposit of a silver layer for an MMT layer that was initially deposited on a Si substrate. The surface morphology and thickness evaluation of deposited biocomposite layers were performed by scanning electron microscopy (SEM). A qualitative analysis of the chemical composition of thin layers was performed and the elements O, Ag, Mg, Fe, Al, and Si were identified in the MMT-Ag biocomposite multilayers. The in vitro antifungal assay proved that the inhibitory effect against the growth of Candida albicans ATCC 101231 CFU was more emphasized in the case of MMT-Ag biocomposite multilayers that in the case of the MMT layer. Cytotoxicity studies performed on HeLa cells showed that the tested layers did not show significant toxicity at the time intervals during which the assay was performed. On the other hand, it was observed that the MMT layers exhibited slightly higher biocompatible properties than the MMT-Ag composite layers. |
| Databáze: | OpenAIRE |
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