Squamous Cell Carcinoma of the Tongue Among Young Indian Adults
| Autor: | P Sebastian, Elizabeth Mathew Iype, Manoj Pandey, Aleyamma Mathew, Gigi Thomas, Madhavan Krishnan Nair |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Brief Article India Disease survival lcsh:RC254-282 Disease-Free Survival Risk Factors Tongue tongue Internal medicine Epidemiology Carcinoma Humans Medicine Stage (cooking) Tongue Neoplasm Demography Retrospective Studies Gynecology treatment business.industry Cancer Retrospective cohort study oral cancer medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Tongue Neoplasms stomatognathic diseases Treatment Outcome medicine.anatomical_structure age Carcinoma Squamous Cell Female epidemiology business Follow-Up Studies |
| Zdroj: | Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 4, Pp 273-277 (2001) |
| ISSN: | 1476-5586 |
| DOI: | 10.1038/sj.neo.7900172 |
| Popis: | Oral cancer is one of the commonest cancers among males in India. This study was carried out to evaluate the demographics, risk profile, clinicopathologic features, and treatment outcome in young patients with squamous cell carcinoma (SCC) of the tongue. Patients under the age of 35 years with SCC of the tongue presenting between 1982 and 1996 were identified using institutions centralized electronic database. Demographic, clinical, and pathologic characteristics were abstracted from the case records. Survival was calculated by Kaplan-Meier method. One hundred and fifteen patients with histologically confirmed SCC of the tongue were analyzed. The mean age at presentation was 30.5 years with a 1.7:1 male to female ratio. Prior exposure to tobacco and alcohol was noted in 58 (50.5%) patients. At presentation, 70 (60.9%) were in stages III and IV, and 59 (51.3%) patients had regional lymph node involvement. The overall disease-free survival (DFS) at 3 and 5 years were 63% and 54.9%, respectively. A statistically significant difference in DFS was seen between patients with No and N, disease compared to N2 or N3 disease. Various other factors like age, sex, habits, and stage of the disease were found to have no significant effect on DFS. Results of the present study suggest that contrary to the belief, the survival among young patients is almost similar to that in older patients. |
| Databáze: | OpenAIRE |
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