Tranexamic Acid Effectiveness on the Amount of Bleeding during Surgery and Surgeon’s Satisfaction in Intertrochanteric Fracture Fixation: A Randomized Clinical Trial
| Autor: | Keykhosro Mardanpour, Seyyed Saeed Khabiri, Morteza Saeb, Monireh Yaghoubi, Alireza Shafiee, Adel Hojabrian, Sepehr Rahimipour, Ali Mousapour, Roya Safari-Faramani, Ali Gholami |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Proximal femur business.industry Hemoglobin levels Placebo Group B Surgery law.invention Tranexamic Acid Hip Fractures Surgical Blood Loss Randomized Controlled Trial Randomized controlled trial law medicine Medicine Intertrochanteric fracture business Tranexamic acid medicine.drug Fixation (histology) |
| Zdroj: | Journal of Orthopedic and Spine Trauma, Vol 5, Iss 1 (2020) |
| ISSN: | 2538-4600 2538-2330 |
| DOI: | 10.18502/jost.v5i1.3319 |
| Popis: | IntroductionThe purpose of this double-blind randomized clinical trial study was the evaluation of intravenous tranexamic acid on hemorrhage volume during Surgery and surgeon's satisfaction in intertrochanteric fracture surgery.Material and MethodsA total of 62 intertrochanteric fractures (AO class 1 to 3) were randomly divided into two groups of 31. In the control group patients (69.2± 6.1 years old) treated with placebo and the intervention group receiving1gr tranexamic acid (69.7± 6.4) have exposed under the surgical operation by lateral approach and proximal femur’s plates., the amount of gauze and post operative blood losses measured with the amount of blood in the drain 48 hours after surgery. Also the hemoglobin levels compared before and after surgery. In the end, Surgeon satisfaction was measured by Likert scale.ResultsThe amount of intraoperative bleeding in suctiondid not differ statistically between the arms (P-value = 0.465).Furthermore, the mean of gauze number in the intervention group was significantly lower than the control group (P-value |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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