How and why researchers use the number needed to vaccinate to inform decision making—A systematic review
| Autor: | Ahmed Hashim, Shelly Bolotin, Vica Dang, Natasha S. Crowcroft |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Cost effectiveness
Cost-Benefit Analysis Decision Making Scientific literature Appropriate use Number needed to vaccinate Mathematicalmodelling Immunology and Microbiology(all) Humans Medicine Generalizability theory Benefits of vaccination Number needed to treat Health Services Needs and Demand Models Statistical Actuarial science General Veterinary General Immunology and Microbiology business.industry Vaccination Public Health Environmental and Occupational Health Viral Vaccines Bacterial Infections veterinary(all) Databases Bibliographic Infectious Diseases Systematic review Research Design Virus Diseases Bacterial Vaccines Molecular Medicine Immunization Cost-effectiveness Observational study business |
| Zdroj: | Vaccine. 33:753-758 |
| ISSN: | 0264-410X |
| DOI: | 10.1016/j.vaccine.2014.12.033 |
| Popis: | Background The number needed to vaccinate (NNV) is a measure that has been widely used in the scientific literature to draw conclusions about the usefulness and cost-effectiveness of various immunization programmes. The main objective of this review is to examine how and why the NNV has been used and reported in the published literature. Methods Electronic databases were searched and records were screened against the eligibility criteria by two independent authors. We included papers that reported and interpreted NNV. Results We identified 27 studies, the designs including observational studies, economic analyses, systematic reviews, and commentaries. The NNV has been used in the literature to describe three main themes: potential benefits of vaccination programmes, cost-effectiveness, and economic analyses, and modelling studies to compare different vaccination strategies. Conclusions NNV has been used in a wide variety of ways in the literature, yet there are no defined thresholds for what is a favourable NNV. Furthermore, the generalizability of the NNV is usually limited. Further work is required to determine the most appropriate use of this measure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect