Body Composition and Its Impact on the Hormonal Disturbances in Women with Polycystic Ovary Syndrome
Autor: | Agnieszka Piwowar, Anna Bizoń, Sylwia Płaczkowska, Dagmara Pluta, Justyna Niepsuj, Marta Czwojdzińska, Grzegorz Franik, Artur Nowak, Paweł Madej, Marcin Leśniewski |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Adult
Anti-Mullerian Hormone Adolescent endocrine system diseases Physiology Logistic regression Article Body Mass Index Young Adult Sex hormone-binding globulin Sex Hormone-Binding Globulin Humans Medicine Testosterone TX341-641 Androstenedione body composition Nutrition and Dietetics hormones Free testosterone biology Nutrition. Foods and food supply business.industry nutritional and metabolic diseases Luteinizing Hormone Polycystic ovary female genital diseases and pregnancy complications Phenotype ROC Curve polycystic ovary syndrome Case-Control Studies biology.protein Female Follicle Stimulating Hormone business Body mass index Food Science Hormone |
Zdroj: | Nutrients; Volume 13; Issue 12; Pages: 4217 Nutrients, Vol 13, Iss 4217, p 4217 (2021) Nutrients |
ISSN: | 2072-6643 |
DOI: | 10.3390/nu13124217 |
Popis: | We investigated the relationship between selected body composition (BC) parameters and included 55 women diagnosed with PCOS and 29 women in which PCOS was excluded. Hormone concentration and BC parameters were assessed during hospitalization. Women with PCOS had higher concentration of luteinizing hormones, total testosterone, androstenedione, and Anti-Müllerian hormones compared to women that were not diagnosed with PCOS. We did not observe any significant differences in the BC parameters between both groups as well as between four PCOS phenotype subgroups. Only in the group of women with PCOS was the concentration of sex hormone binding globulin and free testosterone correlated with all investigated BC parameters. Correspondence analysis did not confirm unambiguously associations between phenotypes of PCOS and the value of BC parameters, while logistic regression revealed that increased Anti-Müllerian hormone concentration and the value of body mass index could be useful parameters in differentiating women with PCOS and women with other disorders. The ROC analysis performed on the entire group of women also confirmed that the concentration of Anti-Müllerian hormones could be a powerful parameter to categorize women as suffering from PCOS. |
Databáze: | OpenAIRE |
Externí odkaz: |
načítá se...