Body Composition and Its Impact on the Hormonal Disturbances in Women with Polycystic Ovary Syndrome

Autor: Agnieszka Piwowar, Anna Bizoń, Sylwia Płaczkowska, Dagmara Pluta, Justyna Niepsuj, Marta Czwojdzińska, Grzegorz Franik, Artur Nowak, Paweł Madej, Marcin Leśniewski
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nutrients; Volume 13; Issue 12; Pages: 4217
Nutrients, Vol 13, Iss 4217, p 4217 (2021)
Nutrients
ISSN: 2072-6643
DOI: 10.3390/nu13124217
Popis: We investigated the relationship between selected body composition (BC) parameters and included 55 women diagnosed with PCOS and 29 women in which PCOS was excluded. Hormone concentration and BC parameters were assessed during hospitalization. Women with PCOS had higher concentration of luteinizing hormones, total testosterone, androstenedione, and Anti-Müllerian hormones compared to women that were not diagnosed with PCOS. We did not observe any significant differences in the BC parameters between both groups as well as between four PCOS phenotype subgroups. Only in the group of women with PCOS was the concentration of sex hormone binding globulin and free testosterone correlated with all investigated BC parameters. Correspondence analysis did not confirm unambiguously associations between phenotypes of PCOS and the value of BC parameters, while logistic regression revealed that increased Anti-Müllerian hormone concentration and the value of body mass index could be useful parameters in differentiating women with PCOS and women with other disorders. The ROC analysis performed on the entire group of women also confirmed that the concentration of Anti-Müllerian hormones could be a powerful parameter to categorize women as suffering from PCOS.
Databáze: OpenAIRE
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