Does the Tube Voltage Affect the Characterization of Coronary Plaques on 100- and 120-kVp Computed Tomography Scans
| Autor: | Takanori Masuda, Yoriaki Matsumoto, Kazuo Awai, Noritaka Noda, Takeshi Nakaura, Yoshinori Funama, Tomoyasu Sato, Tomokazu Okimoto, Naoyuki Imada, Yukari Yamashita |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Computed Tomography Angiography Lumen (anatomy) Coronary Angiography Radiation Dosage 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Hounsfield scale Intravascular ultrasound medicine Cutoff Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test Receiver operating characteristic business.industry Area under the curve Middle Aged Confidence interval Plaque Atherosclerotic ROC Curve Area Under Curve Angiography Female Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of computer assisted tomography. 43(3) |
| ISSN: | 1532-3145 |
| Popis: | Objective The aim of this study was to compare the diagnostic performance of 100- and 120-kVp coronary computed tomography (CT) angiography (CCTA) scans for the identification of coronary plaque components. Methods We included 116 patients with coronary plaques who underwent CCTA and integrated backscatter intravascular ultrasound studies. On 100-kVp scans, we observed 24 fibrous and 24 fatty/fibrofatty plaques; on 120-kVp scans, we noted 27 fibrous and 41 fatty/fibrofatty plaques. We compared the fibrous and the fatty/fibrofatty plaques, the CT number of the coronary lumen, and the radiation dose on scans obtained at 100 and 120 kVp. We also compared the area under the receiver operating characteristic (ROC) curve of the coronary plaques on 100- and 120-kVp scans with their ROC curves on integrated backscatter intravascular ultrasound images. Results The mean CT numbers of fatty and fatty/fibrofatty plaques were 5.71 ± 36.5 and 76.6 ± 33.7 Hounsfield units (HU), respectively, on 100-kVp scans; on 120-kVp scans, they were 13.9 ± 29.4 and 54.5 ± 22.3 HU, respectively. The CT number of the coronary lumen was 323.1 ± 81.2 HU, and the radiation dose was 563.7 ± 81.2 mGy-cm on 100-kVp scans; these values were 279.3 ± 61.8 HU and 819.1 ± 115.1 mGy-cm on 120-kVp scans. The results of ROC curve analysis identified 30.5 HU as the optimal diagnostic cutoff value for 100-kVp scans (area under the curve = 0.93, 95% confidence interval = 0.87-0.99, sensitivity = 95.8%, specificity = 78.9%); for 120-kVp plaque images, the optimal cutoff was 37.4 HU (area under the curve = 0.87, 95% confidence interval = 0.79-0.96, sensitivity = 82.1%, specificity = 85.7%). Conclusions For the discrimination of coronary plaque components, the diagnostic performance of 100- and 120-kVp CCTA scans is comparable. |
| Databáze: | OpenAIRE |
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