The Effect of Dietary Carbohydrate and Fat Manipulation on the Metabolome and Markers of Glucose and Insulin Metabolism: A Randomised Parallel Trial
Autor: | Deaglan McCullough, Tanja Harrison, Lynne M. Boddy, Kevin J. Enright, Farzad Amirabdollahian, Michael A. Schmidt, Katrina Doenges, Kevin Quinn, Nichole Reisdorph, Mohsen Mazidi, Katie E. Lane, Claire E. Stewart, Ian G. Davies |
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Rok vydání: | 2022 |
Předmět: |
Adult
Leptin Nutrition and Dietetics insulin resistance cardiometabolic risk low carbohydrate high-fat diet carbohydrate fat metabolomics R1 Dietary Fats Lipids Diet Carbohydrate-Restricted Glucose Diabetes Mellitus Type 2 Cardiovascular Diseases Dietary Carbohydrates Metabolome Humans Insulin Adiponectin Insulin Resistance Biomarkers Food Science Nutrition |
Zdroj: | Nutrients Nutrients; Volume 14; Issue 18; Pages: 3691 |
ISSN: | 2072-6643 |
Popis: | High carbohydrate, lower fat (HCLF) diets are recommended to reduce cardiometabolic disease (CMD) but low carbohydrate high fat (LCHF) diets can be just as effective. The effect of LCHF on novel insulin resistance biomarkers and the metabolome has not been fully explored. The aim of this study was to investigate the impact of an ad libitum 8-week LCHF diet compared with a HCLF diet on CMD markers, the metabolome, and insulin resistance markers. n = 16 adults were randomly assigned to either LCHF (n = 8 |
Databáze: | OpenAIRE |
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