Design and applications of coupled SPE-CE
| Autor: | Gerhardus J. de Jong, Govert W. Somsen, Willy J. M. Underberg, F. W. Alexander Tempels |
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| Přispěvatelé: | BioAnalytical Chemistry, AIMMS |
| Rok vydání: | 2007 |
| Předmět: |
Coupling
Miniaturization business.industry Computer science Clinical Biochemistry Solid Phase Extraction Analytical chemistry Electrophoresis Capillary Equipment Design ComputerSystemsOrganization_PROCESSORARCHITECTURES Biochemistry Online Systems CE Analytical Chemistry Pharmaceutical Preparations Animals Humans Sensitivity (control systems) SPE coupling Process engineering business Volume concentration |
| Zdroj: | Tempels, F W A, Underberg, W J M, Somsen, G W & de Jong, G J 2008, ' Design and applications of coupled SPE-CE ', Electrophoresis, vol. 29, no. 1, pp. 108-128 . https://doi.org/10.1002/elps.200700149 Electrophoresis, 29(1), 108-128. Wiley-VCH Verlag |
| ISSN: | 0173-0835 |
| DOI: | 10.1002/elps.200700149 |
| Popis: | CE suffers from an inherent low concentration sensitivity. Analyte detection limits can be improved by combining CE with SPE. This paper presents an overview of coupled SPE-CE systems that have been reported in literature. Attention is paid to fundamental aspects of coupling SPE and CE, as well as to important SPE requirements. Interfaces for inline and online coupling with CE are critically discussed, and their mode of operation is outlined. Advantages and limitations of the interfaces are discussed and typical examples are selected. Finally, some future developments are discussed. |
| Databáze: | OpenAIRE |
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