Essential thrombocythemia in a child with elevated thrombopoietin concentrations and skeletal anomalies
| Autor: | Edwin B. Robins, Massoma Niazi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Skeletal anomalies Mothers Physiology Bone and Bones Reactive thrombocytosis hemic and lymphatic diseases medicine Humans Hydroxyurea Platelet Enzyme Inhibitors Thrombopoietin Aspirin Thrombocytosis Platelet Count Essential thrombocythemia business.industry Hematology Anagrelide medicine.disease Pedigree Surgery Oncology Child Preschool Pediatrics Perinatology and Child Health Female business Thrombocythemia Essential medicine.drug |
| Zdroj: | Pediatric Blood & Cancer. 50:859-861 |
| ISSN: | 1545-5017 1545-5009 |
| DOI: | 10.1002/pbc.21218 |
| Popis: | Essential thrombocythemia is a rare myleoproliferative disorder in pediatrics. This myleoproliferative disorder is characterized by excessive proliferation of megakaryocytes and sustained elevation of platelet count. Reactive thrombocytosis is a more common cause of elevated platelet counts among children. We describe a 2-year-old child with essential thrombocythemia, skeletal anomalies, and elevated thrombopoietin concentrations. The child's mother was also subsequently diagnosed with essential thrombocythemia and had elevated thrombopoietin concentrations. Chromosomal studies on the mother, child and other family members were normal. |
| Databáze: | OpenAIRE |
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