Proteomics in drug discovery

Autor:	Rodney M. Hewick, Jack H. Wang
Rok vydání:	1999
Předmět:	Pharmacology Genetics Drug discovery Drug Discovery Proteome Gene expression Protein Expression Profiling Genomics Computational biology Biology Proteomics Genome Protein expression
Zdroj:	Drug discovery today. 4(3)
ISSN:	1878-5832
Popis:	The promise of genomics has dramatically altered the way drug discovery is now viewed. Overshadowed by the exuberance for genomics are the observations that most disease processes and treatments are manifest at the protein level and that there may not be a good correlation between gene expression and protein expression. An alternative and complementary approach to genomics is protein expression profiling – proteomics. The authors describe the technology, its advantages and some applications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8ed20198a9ae5e002bc53164570c60 https://pubmed.ncbi.nlm.nih.gov/10322265 Zobrazit plný text záznamu Full Text from ScienceDirect