Green light extends Drosophila longevity
| Autor: | Jie Shen, Xusheng Luo, Peijing Yang, Boying Liang, Jianying Shan, Honglin Li, Yifan Xu, Zhizhang Yang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Aging Light media_common.quotation_subject Longevity Green-light Biochemistry 03 medical and health sciences 0302 clinical medicine Endocrinology Genetics Animals Drosophila Proteins Red light Molecular Biology Drosophila Caloric Restriction media_common Blue light biology Life span Cell Biology biology.organism_classification Heat stress Cell biology Drosophila melanogaster 030104 developmental biology 030217 neurology & neurosurgery |
| Zdroj: | Experimental Gerontology. 147:111268 |
| ISSN: | 0531-5565 |
| DOI: | 10.1016/j.exger.2021.111268 |
| Popis: | The role of visible light on longevity is incompletely understood. Here we show the effect of visible light in Drosophila melanogaster is wavelength specific. Life span was significantly extended by green light, whereas blue light reduced longevity dramatically, and minor impact was observed with red light. While oxidative stress, heat stress, or caloric restriction does not contribute to the beneficial effect of green light, our study found that the life span extension effect of green light might be mediated by microbiota or photosensitive micronutrients in food medium. In conclusion, we report that green light can extend longevity and present the potential of light as a noninvasive therapy for aging-related diseases. |
| Databáze: | OpenAIRE |
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