Variability in expression of cell surface antigens of Candida albicans during morphogenesis
| Autor: | D L Brawner, J E Cutler |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Antigens
Fungal medicine.drug_class Cellular differentiation Immunology Cell Carbohydrates Morphogenesis Germ tube Monoclonal antibody Microbiology Antigen Candida albicans medicine biology Antibodies Monoclonal Cell Differentiation biology.organism_classification Microscopy Electron Infectious Diseases medicine.anatomical_structure Agglutinins Antigens Surface biology.protein Parasitology Antibody Research Article |
| Zdroj: | Infection and Immunity. 51:337-343 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.51.1.337-343.1986 |
| Popis: | The location and expression of two different cell surface antigens on germinating and nongerminating Candida albicans cells was examined by using transmission electron microscopy after labeling with monoclonal antibodies (H9 or C6) and immunocolloidal gold. Immunodeterminant expression of the two carbohydrate antigens was followed from early germination events through 20 h of development. The determinant detected by H9 antibody, which was initially lost from the mother cell surface and preferentially expressed only on hyphae during the first 4 h of germination, reappeared on the mother cell by 20 h, whereas the antigen detected by antibody C6 was continually expressed on mother cells and germ tubes throughout germination. |
| Databáze: | OpenAIRE |
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