Efficacy and safety of a single-use dual blade goniotomy: 18-month results
| Autor: | Shan McBurney-Lin, Daniel M Vu, Susan M. Wakil, Henry C. Tseng, Mohammed K ElMallah, Faith A. Birnbaum |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Intraocular pressure
medicine.medical_specialty genetic structures medicine.medical_treatment Glaucoma Trabeculectomy 03 medical and health sciences Tonometry Ocular 0302 clinical medicine Ophthalmology Glaucoma surgery medicine Humans Adverse effect Intraocular Pressure Retrospective Studies Single use business.industry Significant difference Cataract surgery medicine.disease eye diseases Sensory Systems Single surgeon Treatment Outcome 030221 ophthalmology & optometry Surgery sense organs business 030217 neurology & neurosurgery |
| Zdroj: | Journal of cataract and refractive surgery. 46(10) |
| ISSN: | 1873-4502 |
| Popis: | PURPOSE To compare the 18-month efficacy and safety of Kahook Dual Blade goniotomy (KDB) in combination with cataract surgery (combined group) or as a standalone procedure (standalone group). SETTING Single surgeon practice. DESIGN Retrospective review study. METHODS A total of 116 eyes of 100 patients underwent KDB by a single well-experienced surgeon from May 2016 to 2018. A total of 93 eyes and 23 eyes were in the combined and standalone groups, respectively. Main outcome measures were reduction in intraocular pressure (IOP) and IOP-lowering medication and adverse events. Data were collected and analyzed using Welch t tests in R. RESULTS A total of 116 eyes of 100 patients were included in the analysis. Moderate or severe glaucoma was observed in 71% of eyes in the combined group compared with 83% in the standalone group. At baseline, mean IOP was 16.5 ± 5.0 mm Hg (n = 93) and 24.3 ± 9.1 mm Hg (n = 23) in the combined and standalone groups, respectively (P < .05). The IOP decreased in both groups at 12 months (14.1 ± 3.9 vs 16.9 ± 7.6, P = .24) and 18 months (14.4 ± 3.7 vs 16.7 ± 7.6, P = .5). There was a statistically significant difference in the number of drops between the combined and standalone groups at baseline (2.4 ± 1.2 vs 2.9 ± 1.0, P < .05) persisting at 12 months (1.3 ± 1.2 vs 2.6 ± 1.2, P < .05) and at 18 months (1.3 ± 1.2 vs 3.3 ± 1.2, P < .05). Complications included transient hyphemas (20 eyes [17%]) and IOP spike (20 eyes [17%]). Seven eyes required additional glaucoma surgery, 5 of which were in the standalone group. CONCLUSIONS KDB was an effective and safe procedure for different glaucoma disease severities, whether combined with cataract surgery or as a standalone surgery. It is an alternative to consider prior to pursuing more invasive glaucoma surgeries. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|