Association between chronic bladder catheterisation and bladder cancer incidence and mortality: a population-based retrospective cohort study in Ontario, Canada
| Autor: | Ronald T. Kodama, Lesley K. Carr, Girish S. Kulkarni, Refik Saskin, Amanda Hird, Steven A. Narod, Rano Matta, Yuna Lee, Ying Liu, Robert K. Nam, Khaled Ajib, Sender Herschorn |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Urinary system Population urologic and male genital diseases Cohort Studies Catheters Indwelling Internal medicine medicine Humans education bladder disorders Retrospective Studies Ontario education.field_of_study urological tumours Bladder cancer business.industry Incidence (epidemiology) Incidence urolithiasis Retrospective cohort study General Medicine Middle Aged medicine.disease female genital diseases and pregnancy complications Catheter Oncology Urinary Bladder Neoplasms Cohort Urinary Tract Infections Bladder Disorder Medicine Female business Urinary Catheterization |
| Zdroj: | BMJ Open BMJ Open, Vol 11, Iss 9 (2021) |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesTo compare the risk of bladder cancer and bladder cancer mortality among patients with chronic bladder catheterisation (indwelling or intermittent) to patients from the general population.DesignRetrospective cohort study.SettingPopulation-based study in Ontario, Canada between 2003 and 2018.ParticipantsAdult patients 18–90 years of age with chronic bladder catheterisation were hard matched to patients from the general population without a history of bladder catheterisation.InterventionsThe presence of a chronic catheter was defined as a minimum of two physician encounters for bladder catheterisation, suprapubic tube insertion or home care for catheter care separated by at least 28 days. Urinary tract infection (UTI) rates were collected.Main outcome measuresBladder cancer and bladder cancer-specific mortality after a 1-year lag period were compared between groups.ResultsWe identified 36 903 patients with chronic catheterisation matched to 110 709 patients without a history of catheterisation. Patients were followed for a median of 8.8 years (IQR: 5.2–11.9 years). The median age was 62 years (IQR: 50–71) and 52% were female. More patients in the catheter group developed bladder cancer (393 (1.1%) vs 304 (0.3%),pConclusionsThis is the first study to quantify the increase in bladder cancer incidence and mortality in a large, diverse cohort of patients with chronic indwelling or intermittent bladder catheterisation. The risk was highest among patients with a chronic catheter beyond 2.9 years. |
| Databáze: | OpenAIRE |
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