Argonaute and GW182 proteins: an effective alliance in gene silencing

Autor:	Gunter Meister, Janina Pfaff
Rok vydání:	2013
Předmět:	Genetics Protein family RNA-induced silencing complex Trans-acting siRNA Argonaute Biology Biochemistry F-box protein Cell biology Argonaute Proteins biology.protein RNA RasiRNA Gene silencing Gene Silencing Protein Binding RDE-1
Zdroj:	Biochemical Society Transactions. 41:855-860
ISSN:	1470-8752 0300-5127
Popis:	Argonaute proteins interact with small RNAs and facilitate small RNA-guided gene-silencing processes. Small RNAs guide Argonaute proteins to distinct target sites on mRNAs where Argonaute proteins interact with members of the GW182 protein family (also known as GW proteins). In subsequent steps, GW182 proteins mediate the downstream steps of gene silencing. The present mini-review summarizes and discusses our current knowledge of the molecular basis of Argonaute–GW182 protein interactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6e6f6120e07516ec9c5ac1587c218b https://doi.org/10.1042/bst20130047 Zobrazit plný text záznamu