Dynamic changes in near-infrared spectroscopy (NIRS) findings in first-episode schizophrenia: a case report
Autor: | Rieko Suzuki, Yasuto Kunii, Hirooki Yabe, Sachie Oshima, Tsuyoshi Hatakeyama, Shuntaro Itagaki, Keiko Nozaki, Tetsuya Shiga, Itaru Miura, Soichi Kono |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Pediatrics
medicine.medical_specialty Adolescent near-infrared spectroscopy Case Report First episode schizophrenia behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine mental disorders medicine Humans Cortical surface Frontal region State marker Psychiatry 493.7 Brain function Blood Volume Spectroscopy Near-Infrared business.industry Clinical course homovanillic acid General Medicine medicine.disease 030227 psychiatry schizophrenia state marker Schizophrenia Cerebrovascular Circulation Oxyhemoglobins Acute Disease biomarker Female business Biomarkers 030217 neurology & neurosurgery Antipsychotic Agents Diagnosis of schizophrenia |
Zdroj: | Fukushima Journal of Medical Science. 63(1):28-31 |
ISSN: | 0016-2590 |
Popis: | The clinical course of schizophrenia is characterized by recurrence and chronicity and has a large burden on society. Nevertheless, diagnosis of schizophrenia is based only on distinctive symptoms and the disease course. Near-infrared spectroscopy (NIRS) is a useful method for measuring changes in the hemoglobin concentration in the cortical surface area and reflects brain function. We measured NIRS four times during the clinical course in a patient with first-episode schizophrenia. A 17-year-old woman admitted to our hospital because of hallucinations, delusions and appetite loss. After treatment with low-dose antipsychotics, NIRS findings showed a prompt increase in the cerebral blood volume in the frontal region. On the basis of the clinical course of this patient, we introduce a new point of view, namely, that NIRS findings may be useful as a state marker that indicates the severity of schizophrenia in some cases. |
Databáze: | OpenAIRE |
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