The complete genome sequence of the lumpy skin disease virus vaccine Herbivac LS reveals a mutation in the superoxide dismutase gene homolog
| Autor: | Nicola Douglass, Henry Munyanduki, Ruzaiq Omar, Anna-Lise Williamson, Anelda van der Walt |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Locus (genetics) Biology Superoxide dismutase Viral Proteins 03 medical and health sciences Vaccine strain Medical microbiology Genome Size Virology medicine Animals Gene Homolog Genome size 030304 developmental biology Whole genome sequencing 0303 health sciences Whole Genome Sequencing Superoxide Dismutase 030306 microbiology Viral Vaccines General Medicine Lumpy skin disease virus Mutation biology.protein Cattle |
| Zdroj: | Archives of Virology. 164:3107-3109 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/s00705-019-04405-8 |
| Popis: | The lumpy skin disease virus (LSDV) vaccine, Herbivac LS, batch 008, was sequenced and found to differ from the Neethling vaccine strain in the locus encoding a superoxide dismutase (SOD) homolog. The presence of a SOD homolog, be it full-length (as in Herbivac LS) or truncated (as in Neethling) may affect vaccine immunogenicity. |
| Databáze: | OpenAIRE |
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