The Role of Nutrition in the Etiology of Inflammatory Bowel Disease
| Autor: | Dietmar Scholz |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Adolescent Breastfeeding Disease Enteral administration Inflammatory bowel disease Gastroenterology Enteral Nutrition Meta-Analysis as Topic Adrenal Cortex Hormones Recurrence Internal medicine Fatty Acids Omega-3 medicine Humans Medical nutrition therapy Child Intensive care medicine business.industry General Medicine Inflammatory Bowel Diseases medicine.disease Ulcerative colitis Nutrigenomics Child Preschool Pediatrics Perinatology and Child Health Etiology Nutrition Therapy Child Nutritional Physiological Phenomena business |
| Zdroj: | Current Problems in Pediatric and Adolescent Health Care. 41:248-253 |
| ISSN: | 1538-5442 |
| DOI: | 10.1016/j.cppeds.2011.04.005 |
| Popis: | Many foods have been implicated in theories about the etiology of inflammatory bowel disease. While evidence has accumulated that nutritional factors as part of overall lifestyle changes may play a role in the growing incidence, no specific dietary recommendations except the promotion of breastfeeding can currently be given to decrease the risk of developing Crohn's disease or ulcerative colitis. For the treatment of Crohn's disease in children and adolescents, however, enteral feeding with a semi-elemental diet seems to be as effective as corticosteroids in inducing and maintaining remission. In the meta-analyses, advantages of one formula over the other are evened out, and more research is warranted into the anti-inflammatory properties of different nutrients, such as polyunsaturated fatty acids, butyrate, glutamine, and cytokines, such as transforming growth factors-beta. Unfortunately, for practical reasons, nutritional therapy remains underutilized, even though pediatric patients are most vulnerable to the harmful effects of nutrient deficiencies on growth, pubertal development, and bone health. There is hope that in the future the new field of nutrigenomics may enable physicians to more accurately tailor a specific diet to the patient genotype. |
| Databáze: | OpenAIRE |
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