Molecular phylogeny of modern coxsackievirus A16
| Autor: | Pilaipan Puthavathana, Peter C. McMinn, M. A. Yusof, Y. A. Malik, K.K. Wong, K. B. Chua, Phan Van Tu, Nguyen Thi Thanh Thao, Nguyen Thi Kim Tien, Mary Jane Cardosa, Mong How Ooi, A. Zaki, David Perera, Yuwana Podin |
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| Rok vydání: | 2007 |
| Předmět: |
viruses
Lineage (evolution) Molecular Sequence Data Biology medicine.disease_cause Virus Evolution Molecular fluids and secretions Phylogenetics Virology medicine Humans Nucleotide Phylogeny DNA Primers Viral Structural Proteins chemistry.chemical_classification Genetics Base Sequence Strain (chemistry) Phylogenetic tree virus diseases General Medicine Enterovirus A Human chemistry DNA Viral Molecular phylogenetics Enterovirus Capsid Proteins Hand Foot and Mouth Disease |
| Zdroj: | Archives of Virology. 152:1201-1208 |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7-30.2% and 19.9-25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains. |
| Databáze: | OpenAIRE |
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