| Autor: |
Reagan, Resadita, M Rosadi, Seswandhana, Eko, Purnomo, Sharfan, Anzhari, Gita Christy, Gabriela, Ishandono, Dachlan, Teguh, Aryandono, Yohanes Widodo, Wirohadidjojo |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Annals of Medicine & Surgery. 75 |
| ISSN: |
2049-0801 |
| Popis: |
Sepsis is one of the main causes in burn victim's mortality. The use of negative pressure wound therapy (NPWT) provides an ideal environment to accelerate wound healing. We compare the use of normal saline (NS), intermittent NPWT, continuous NPWT and silver sulfadiazine in wound healing process.This study involved 6 Yorkshire pigs; each pig was induced with 20 burns on the flank area. Burns were divided into 4 treatment groups: NS gauze, intermittent NPWT, continuous NPWT, and silver sulfadiazine dressing. Burns were evaluated on day 1,3,7,14, and 21 for its morphology and bacterial colonization and on day 14 and 21 for the remaining burn surface area.Wound that received NPWT therapy appeared better in both granulation and crust formation. Remaining burn surface area (mmWhile morphologically, the wound in NPWT treatment groups appeared better in granulation and crust formation, the remaining wound surface area and the number of bacterial colonization were not significantly difference compared to standard therapy (silver sulfadiazine and NS gauze). There were no significant correlation between the amount of bacterial colonization and remaining wound surface area on every treatment group. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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