A Web-Based System for the Quantitative and Reproducible Assessment of Clinical Indexes From the Retinal Vasculature

Autor: D. Fiorin, Enea Poletti, Alfredo Ruggeri, Lara Tramontan
Rok vydání: 2011
Předmět:
Zdroj: IEEE Transactions on Biomedical Engineering. 58:818-821
ISSN: 1558-2531
0018-9294
DOI: 10.1109/tbme.2010.2085001
Popis: A novel system for the vascular tree identification and the quantitative estimation of arteriolar venular ratio clinical index in retinal fundus images is presented. The system is composed of a module for automatic vascular tracking, an interactive editing interface to correct errors and set the required parameters of analysis, and a module for the computation of clinical indexes. The system was organized as a client-server structure to allow clinicians and researchers from all over the world to work remotely. The system was evaluated by three graders analyzing 30 fundus images. The evaluation of the Pearson's correlation coefficient and p-value of a paired t-test for each pair of graders demonstrates the high reproducibility of the measures provided by the system.
Databáze: OpenAIRE