Impact of 'opening the lung' ventilatory strategy on burn patients with acute respiratory distress syndrome
| Autor: | Nguyen Nhu Lam, Tran Dinh Hung, Dong Khac Hung |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male ARDS Time Factors Acute respiratory distress Critical Care and Intensive Care Medicine Volume control Positive-Pressure Respiration Humans Weaning Medicine Prospective Studies Mortality Prospective cohort study Lung Compliance Respiratory Distress Syndrome Duration of Therapy Lung business.industry General Medicine Oxygenation Length of Stay Smoke Inhalation Injury respiratory system medicine.disease Respiration Artificial respiratory tract diseases Intensive Care Units medicine.anatomical_structure Anesthesia Emergency Medicine Breathing Female Surgery Blood Gas Analysis Burns business Ventilator Weaning |
| Zdroj: | Burns. 45:1841-1847 |
| ISSN: | 0305-4179 |
| Popis: | Objective The objective of this study was to investigate the feasibility and influence of opening the lung strategy ventilation on burned patients complicated with ARDS. Methods A prospective study was carried out in 66 moderate to severe burned patients also presented with ARDS who were randomly divided into the control group (ventilated as ARDS net) and the study group (ventilated with open lung strategy). All patients were ventilated with volume control mode until weaning. Results Opening the lung procedure was safe in all patients with optimal PEEP of 14.8 ± 1.8 cmH2O. After 24 h of lung recruitment and PEEP titration, oxygenation significantly improved (PaO2/FiO2 ratio increased from 119.8 ± 7.4 to 263.4 ± 11.6; p 0.05). In addition, duration time from ADRS onset to death and from admission to death were also remarkably longer in the study group (p Conclusion It is necessary to conduct further trials to find out the effectiveness of this ventilation strategy on burns injury induced ARDS. |
| Databáze: | OpenAIRE |
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