Potential value of T1 mapping in cardiac MR assessment of hypertrophic cardiomyopathy and dilated cardiomyopathy patients: preliminary results
| Autor: | Boris Maurel, Alexandros Kallifatidis, Franck Thuny, Guy Moulin, Jean Michel Bartoli, Alexis Jacquier |
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| Rok vydání: | 2012 |
| Předmět: |
Medicine(all)
medicine.medical_specialty Pathology Radiological and Ultrasound Technology business.industry Hypertrophic cardiomyopathy Dilated cardiomyopathy medicine.disease Fibrosis Internal medicine Poster Presentation cardiovascular system medicine Cardiology Radiology Nuclear Medicine and imaging Myocardial fibrosis cardiovascular diseases Cardiology and Cardiovascular Medicine business Pathological Angiology |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance |
| ISSN: | 1532-429X |
| DOI: | 10.1186/1532-429x-14-s1-p145 |
| Popis: | Summary The purpose of this study is to assess the potential value of T1 mapping in assessing fibrosis in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in comparison to late contrast enhanced imaging using cardiac MR. Background Myocardial fibrosis causes 1) increased stiffness and induces pathological signaling in cardiomyocytes resulting in progressive cardiac failure, 2)impairs mechanoelectric coupling of cardiomyocytes and increases the risk of arrhythmias. T1 mapping allow to quantify the total amount of myocardial extracellular volume and to subsequently define the amount of myocardial fibrosis. Quantification of fibrosis in dilated and hypertrophic cardiomyopathies and it’s link to delayed myocardial enhancement is unclear. Methods |
| Databáze: | OpenAIRE |
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