Long-term follow-up of non-calcified pulmonary nodules (10 mm) identified during low-dose CT screening for lung cancer
| Autor: | Dermot Kenny, P. Mark Logan, Michael M. Slattery, Michael J. Lee, Claire Foley, Richard W. Costello |
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| Rok vydání: | 2011 |
| Předmět: |
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medicine.medical_specialty Radiation Dosage Risk Factors Prevalence Medicine Humans Mass Screening Radiology Nuclear Medicine and imaging Lung cancer Neuroradiology Aged Multiple Pulmonary Nodules Solitary pulmonary nodule medicine.diagnostic_test business.industry Ultrasound Calcinosis Solitary Pulmonary Nodule Interventional radiology General Medicine Middle Aged medicine.disease Female Radiology Tomography business Tomography X-Ray Computed Ireland Lung cancer screening Follow-Up Studies |
| Zdroj: | European radiology. 22(9) |
| ISSN: | 1432-1084 |
| Popis: | To assess the long-term stability of small (10 mm) non-calcified pulmonary nodules (NCNs) in high-risk subjects initially screened for lung cancer using low-dose chest computed tomography (LDCCT).A total of 449 subjects initially underwent screening with serial LDCCT over a 2-year period. Participants identified as having NCNs ≥10 mm were referred for formal lung cancer workup. NCNs10 mm diameter were followed in accordance with the study protocol. Seven years after baseline screening, subjects with previously documented NCNs10 mm, which were unchanged in size after the 2-year follow-up period, were re-imaged using LDCCT to assess for interval nodule growth.Eighty-three subjects with previously documented stable NCNs10 mm underwent LDCCT at 7 years. NCNs were unchanged in 78 subjects and had decreased in size in 4 subjects. There was interval growth of an NCN (from 6 mm to 9 mm) in one subject re-imaged at 7 years, but this nodule has remained stable in size over a further 2-year follow-up period.Non-calcified pulmonary nodules10 mm in size that are unchanged in size or smaller after 2 years of follow-up with LDCCT are most likely benign. |
| Databáze: | OpenAIRE |
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