Superficial temporal artery biopsy diagnostic for lung carcinoma

Autor: Ramin Monshizadeh, Homayoun Tabandeh, M. Tariq Bhatti, Jaime Furman, Shailesh K Gupta
Rok vydání: 2001
Předmět:
Zdroj: American Journal of Ophthalmology. 132:135-138
ISSN: 0002-9394
DOI: 10.1016/s0002-9394(00)00953-3
Popis: PURPOSE: To report a unique finding of metastatic tumor cells in the lumen of a superficial temporal artery biopsy specimen in a patient with severe visual loss and optic neuropathy. METHODS: Case report. RESULTS: A 69-year-old man presented with anorexia, pancranial headaches, and acute unilateral visual loss. Ophthalmic examination showed a visual acuity of no light perception and an amaurotic pupil in the left eye. Fundus examination was normal. A superficial temporal artery biopsy, performed for presumed arteritic posterior ischemic optic neuropathy, demonstrated intraluminal cells with irregular nuclei and prominent nucleoli suggestive of metastatic malignancy. Further systemic evaluation uncovered a poorly differentiated adenocarcinoma of the lung with intravascular infiltration and multiple distant metastases. CONCLUSION: Extensive systemic intravascular tumor embolization may be associated with optic neuropathy.
Databáze: OpenAIRE