Proteomic Profiling of Liver from Atlantic Salmon (Salmo salar) Fed Genetically Modified Soy Compared to the Near-Isogenic non-GM Line
| Autor: | Nini H. Sissener, Monica Sanden, Samuel A.M. Martin, Gro-Ingunn Hemre, Ernst M. Hevrøy, Phillip Cash |
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| Rok vydání: | 2009 |
| Předmět: |
Proteomics
Expressed sequence tag Two-dimensional gel electrophoresis Food Genetically Modified Salmo salar Genetically modified crops Biology Plants Genetically Modified biology.organism_classification Animal Feed Applied Microbiology and Biotechnology Molecular biology Diet law.invention Genetically modified organism Gene Expression Regulation law Proteome Animals Animal Nutritional Physiological Phenomena Soybeans Salmo Energy Intake Polymerase chain reaction |
| Zdroj: | Marine Biotechnology. 12:273-281 |
| ISSN: | 1436-2236 1436-2228 |
| DOI: | 10.1007/s10126-009-9214-1 |
| Popis: | The aim of this study was to investigate potential differences in liver protein expression of Atlantic salmon fed genetically modified (GM) Roundup Ready® soy at a high inclusion level (25% inclusion, constituting 21% of crude protein in the diet) for 7 months or a compositionally similar non-GM diet. The liver was selected as the target organ due to its importance in the general metabolism, and 2D gel electrophoresis used as a screening tool. Samples from 12 individual fish from each diet group were evaluated. Of a total of 781 analysed protein spots, only 36 were significantly different by ANOVA (p |
| Databáze: | OpenAIRE |
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