Intra peritoneal abdominal fat area measured from computed tomography is an independent factor of severe acute pancreatitis
| Autor: | Jean-Pierre Tasu, G. Vesselle, G. Herpe, C. Sylvain, David Tougeron, Pierre Ingrand, S. Boucebci, C. Madico |
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| Přispěvatelé: | Centre hospitalier universitaire de Poitiers (CHU Poitiers), Université de Poitiers |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Intra peritoneal Umbilicus (mollusc) [SDV]Life Sciences [q-bio] Contrast Media Computed tomography Intra-Abdominal Fat Gastroenterology Severity of Illness Index 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine medicine Abdominal fat Humans Radiology Nuclear Medicine and imaging Visceral fat Aged Retrospective Studies Aged 80 and over Univariate analysis Radiological and Ultrasound Technology medicine.diagnostic_test business.industry General Medicine Length of Stay Middle Aged medicine.disease Independent factor Pancreatitis 030220 oncology & carcinogenesis Acute pancreatitis Female business Tomography X-Ray Computed |
| Zdroj: | Diagnostic and Interventional Imaging Diagnostic and Interventional Imaging, Elsevier, 2019, 100, pp.421-426. ⟨10.1016/j.diii.2019.03.008⟩ |
| ISSN: | 2211-5684 |
| DOI: | 10.1016/j.diii.2019.03.008⟩ |
| Popis: | Purpose The purpose of this study was to search for a possible relationship between acute pancreatitis (AP) severity and visceral fat (VF) surface on contrast-enhanced computed tomography (CECT). Material and method A total of 112 patients with AP who underwent CECT within 2 to 3 days after the beginning of AP were included. There were 68 mean and 44 women, with a mean age of 56.3 ± 21.6 (SD) years (range: 19–98 years). AP was regarded as mild for patients with an hospital stay up to 5 days and severe for those with an hospital stay greater than 5 days. VF surface was measured on CECT at the level of L4-L5 and of the umbilicus. Association between AP severity and VF surface, computed tomography severity index (CTSI), modified CTSI (mCTSI) and other variables were searched for using uni- and multivariate analysis. Results At univariate analysis, the VF surface at the level of L4 was greater in patients with severe AP (129.3 ± 68.6 [SD] cm2; range: 21.8-355.8 cm2) than in patients with mild AP (100.1 ± 68.4 [SD] cm2; range:13.2–333 cm2) (P = 0.006). Similarly, the VF surface at the umbilicus was greater in patients with severe AP (161.1 ± 76.1 [SD] cm2; range: 31.3–376.7 cm2) than in those with mild AP (128.4 ± 74.3 cm2; range: 12.8-323.1 cm2) (P = 0.024). CTSI and mCTSI were also associated to AP severity. At multivariate analysis, only VF surface either measured at the umbilical or at the L4-L5 level was associated with AP severity (P = 0.017 and 0.006, respectively). Conclusion VF surface at the level of L4–L5 on CECT is an independent factor of AP severity. VF surface at the level of L4–L5 on CECT is an independent factor of AP severity. These results are in line with recent data on the role of abdominal fat in the genesis of inflammatory response, which is associated with severe forms of AP. |
| Databáze: | OpenAIRE |
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