Hyperprolactinemia in systemic lupus erythematosus?
| Autor: | R. Santen, Matthias Schneider, R. Fischer, Ch. Specker, B. Ostendorf, B. Schmitz-Linneweber |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Systemic disease Adolescent Immunology Blood Sedimentation Severity of Illness Index Cohort Studies Basal (phylogenetics) Rheumatology immune system diseases Internal medicine Immunopathology medicine Prevalence Immunology and Allergy Humans Lupus Erythematosus Systemic skin and connective tissue diseases Aged Autoimmune disease Lupus erythematosus business.industry General Medicine Middle Aged medicine.disease Connective tissue disease Prolactin Hyperprolactinemia Endocrinology Cohort Female business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Scandinavian journal of rheumatology. 25(2) |
| ISSN: | 0300-9742 |
| Popis: | The objective of this project was to determine the prevalence of hyperprolactinemia (HPRL) in systemic lupus erythematosus (SLE) and to evaluate the role of prolactin (PRL) as a disease-activity marker. We determined PRL in a cohort of 182 patients with SLE. Basal prolactin levels and clinical data (disease-activity index, sero-activity, medications) were analyzed in all patients. The findings show only mildly elevated PRL levels in four SLE-patients and normaprolactinemia in 98% (n = 178), without any association with disease activity. Our results differ from previous studies. HPRL appears not to be prevalent in SLE, nor to be associated with disease activity. |
| Databáze: | OpenAIRE |
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