Enantioselective Synthesis of Alkyl Allyl Ethers via Palladium‐Catalyzed Redox‐Relay Heck Alkenylation of O ‐Alkyl Enol Ethers
| Autor: | Matthew B. Prater, Matthew S. Sigman |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry organic chemicals education Enantioselective synthesis chemistry.chemical_element General Chemistry Bond formation 010402 general chemistry 01 natural sciences Enol Medicinal chemistry Redox Article 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Heck reaction Alkyl Palladium |
| Zdroj: | Isr J Chem |
| ISSN: | 1869-5868 0021-2148 |
| DOI: | 10.1002/ijch.201900077 |
| Popis: | Herein we report a transformation that generates an array of enantiomerically enriched, alkyl allyl ethers. Cyclic, acyclic, and heteroatom-bearing alkenyl triflates undergo an enantioselective, palladium-catalyzed C–C bond formation with diverse acyclic O-alkyl enol ethers in good yields and excellent enantioselectivities. |
| Databáze: | OpenAIRE |
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