Interaction Mechanisms and Interface Configuration of Cysteine Adsorbed on Gold, Silver, and Copper Nanoparticles

Autor:	Penélope Rodríguez-Zamora, Cédric A. Cordero-Silis, Jorge Fabila, Jonathan Casildo Luque-Ceballos, Fernando Buendía, Alejandro Heredia-Barbero, Ignacio L. Garzón
Rok vydání:	2022
Předmět:	Silver Electrochemistry Metal Nanoparticles General Materials Science Adsorption Cysteine Gold Surfaces and Interfaces Spectrum Analysis Raman Condensed Matter Physics Copper Spectroscopy
Zdroj:	Langmuir. 38:5418-5427
ISSN:	1520-5827 0743-7463
DOI:	10.1021/acs.langmuir.1c03298
Popis:	Cysteine-protected metal nanoparticles (NPs) have shown interesting physicochemical properties of potential utility in biomedical applications and in the understanding of protein folding. Herein, cysteine interaction with gold, silver, and copper NPs is characterized by Raman spectroscopy and density functional theory calculations to elucidate the molecular conformation and adsorption sites for each metal. The experimental analysis of Raman spectra upon adsorption with respect to free cysteine indicates that while the C-S bond and carboxyl group are similarly affected by adsorption on the three metal NPs, the amino group is sterically influenced by the electronegativity of each metal, causing a greater modification in the case of gold NPs. A theoretical approach that takes into consideration intermolecular interactions using two cysteine molecules is proposed using a S-metal-S interface motif anchored to the metal surface. These interactions generate the stabilization of an organo-metallic complex that combines gauche (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd26d758577fb8142eb1e30e0a40e505 https://doi.org/10.1021/acs.langmuir.1c03298 Zobrazit plný text záznamu