Cancer of unknown primary ultimately diagnosed as male breast cancer: A rare case report
| Autor: | Antonios Tsimpidakis, Evangelia Razis, Georgios Rigakos, Anastasia Vernadou, Sotirios Papadopoulos, Amanda Vakos, Dionysios Papachristou |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Oncology CA15-3 Cancer Research medicine.medical_specialty male breast cancer Lesion 03 medical and health sciences 0302 clinical medicine Internal medicine Back pain medicine microRNA profile Pathological business.industry Cancer Articles medicine.disease Primary tumor cancer of unknown primary 030104 developmental biology Cancer of unknown primary 030220 oncology & carcinogenesis Male breast cancer medicine.symptom business |
| Zdroj: | Molecular and Clinical Oncology |
| ISSN: | 2049-9469 2049-9450 |
| DOI: | 10.3892/mco.2016.912 |
| Popis: | Cancers of unknown primary (CUP) constitute a significant diagnostic and therapeutic challenge for clinicians and a frequent cause of cancer-related mortality in Western countries. Immunohistochemistry assays are commonly used to identify the primary cancer, but fail in approximately one-third of cases. The identification of the possible origin of CUP is crucial, as it may help select the appropriate treatment options. We herein present the case of a 54-year-old male patient, who presented with lower back pain in June, 2013. Following a thorough investigation, the clinical and pathological findings could not identify the primary cancer, leading towards a misdiagnosis. Ultimately, microRNA testing of the resected spine lesion was able to identify the primary tumor as male breast cancer and allow for optimal treatment of the patient. |
| Databáze: | OpenAIRE |
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